Association between glycemic control and morning blood pressure surge with vascular endothelial dysfunction in type 2 DM patients

Diabetes Care:  December 2, 2013

Objective Morning blood pressure surge (MBPS) is an independent predictor of cardiovascular events. However, little is known on the association between glycemic control and MBPS and its effect on vascular injury in patients with type 2 diabetes mellitus (T2DM). The present study examined the association between glycemic control and MBPS and the involvement of MBPS in the development of vascular dysfunction in T2DM patients.

Research Design and Methods We examined MBPS in T2DM patients (M/F; 25/25, age; 60.1±13.2 years, n=50) by 24-hour ambulatory blood pressure monitoring, and assessed vascular function by brachial artery flow-mediated dilation (FMD) and nitroglycerin-mediated dilation (NMD). Read More