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Diversity in Clinical and Biomedical Research: A Promise Yet to Be Fulfilled

Diversity in Clinical and Biomedical Research: A Promise Yet to Be Fulfilled

PLoS Medicine, 15 December 2015 Summary Points Health disparities persist across race/ethnicity for the majority of Healthy People 2010 health indicators. Most physicians and scientists are informed by research extrapolated from a largely homogenous population, usually white and male. A growing proportion of Americans are not fully benefiting from clinical and biomedical advances since racial and ethnic […]

Who’s in Clinical Trials?

U.S. Food and Drug Administration, 9 December 2015 Have you ever wondered if someone like you participated in the clinical trials for a new drug? If you…

Addressing Health Disparities through Clinical Trials

Media Planet: Future of Health Care, December 2015 Historically, participants in clinical trials have not proportionally represented the diversity of our population. This is a stat…

A literature review on the representativeness of randomized controlled trial samples and implications for the external validity of trial results

Trials, 3 Novmber 2015 Randomized controlled trials (RCTs) are conducted under idealized and rigorously controlled conditions that may compromise their external validity. A literature review was conducted…

Introducing clinical research participation to the everyday person

The Catalyst, 15 October 2015 Clinical trials involve many different people and institutions coming together to better understand disease, biology and the impact of potential medicines. Carefully…

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Clinical Research Versus Medical Treatment

Clinical Research Versus Medical Treatment

FDA: 8/5/14 What is clinical research? Clinical research refers to studies in which people participate as patients or volunteers.…

Personalized Medicine and Companion Diagnostics Go Hand-in-Hand

FDA: 7/31/14 Personalized medicine is an evolving field of medicine in which treatments are tailored to the individual…

Publication of Pivotal Efficacy Trials for Novel Therapeutic Agents Approved Between 2005 and 2011

JAMA: July 28, 2014 Pivotal efficacy trials, which are trials that form the basis of the US Food and Drug Administration’s…

Accumulating Research: A Systematic Account of How Cumulative Meta-Analyses Would Have Provided Knowledge, Improved Health, Reduced Harm and Saved Resources

PLOS: July 28, 2014 Abstract Background “Cumulative meta-analysis” describes a statistical procedure to calculate, retrospectively, summary estimates from the…

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