The 10-Year Cost-Effectiveness of Lifestyle Intervention or Metformin for Diabetes Prevention

An intent-to-treat analysis of the DPP/DPPOS March 30, 2012.


OBJECTIVE The Diabetes Prevention Program (DPP) and its Outcomes Study (DPPOS) demonstrated that either intensive lifestyle intervention or metformin could prevent type 2 diabetes in high-risk adults for at least 10 years after randomization. We report the 10-year within-trial cost-effectiveness of the interventions.

RESEARCH DESIGN AND METHODS Data on resource utilization, cost, and quality of life were collected prospectively. Economic analyses were performed from health system and societal perspectives. Read More