Time to Publication Among Completed Clinical Trials

JAMA Intern Medicine: March 4, 2013

Prior studies have shown that 25% to 50% of clinical trials are never published. However, among those published, we know little about the length of time required for publication in the peer-reviewed biomedical literature after study completion. Ioannidis previously demonstrated that a sample of randomized phase 2 and 3 trials conducted between 1986 and 1996 required nearly 2.5 years for publication, while our more recent study of National Institutes of Health (NIH)-funded trials found that the average time to publication was almost 2 years. We sought to determine time to publication for a recent and representative sample of trials published in 2009. Read more